Description

Benzeneacetic Acid, 5-Fluoro-2-Nitro-, Methyl Ester CAS NO 29640-99-1 is a specialized fluorinated nitroaromatic ester, a key building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which facilitates the introduction of both fluorine and nitro functional groups into target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Employed in the synthesis of specialty polymers and advanced organic materials requiring specific electronic properties.
• Fluorination Reagent Building Block: Acts as a source for introducing the 5-fluoro-2-nitrophenyl moiety into more complex molecular structures.

Basic Information

Product Name	Benzeneacetic Acid, 5-Fluoro-2-Nitro-, Methyl Ester
CAS No.	29640-99-1
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Methyl (5-Fluoro-2-nitrophenyl)acetate; (5-Fluoro-2-nitrophenyl)acetic acid methyl ester; 2-(5-Fluoro-2-nitrophenyl)acetic acid methyl ester; Methyl 2-(5-fluoro-2-nitrophenyl)acetate; 5-Fluoro-2-nitrobenzeneacetic acid methyl ester; α-(5-Fluoro-2-nitrophenyl)acetic acid methyl ester; Methyl 5-fluoro-2-nitrobenzeneacetate
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 5-Fluoro-2-Nitro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.