Description

(2S,4S,5R)-2,4,5,6-Tetrahydroxyhexanoic Acid is a high-purity, stereochemically defined polyhydroxy acid with significant utility in advanced chemical synthesis and life science research. Its precise stereochemistry makes it a valuable chiral building block and intermediate for the production of complex molecules, including pharmaceuticals, fine chemicals, and specialty carbohydrates. This compound is particularly relevant for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors seeking high-quality, structurally defined intermediates for process development and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of antiviral agents, antibiotics, and other active pharmaceutical ingredients (APIs) requiring specific stereocenters.
• Biochemical Research: Used as a precursor or standard in the study of carbohydrate metabolism, enzyme inhibitors, and glycobiology.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex natural product analogs, ligands for catalysis, and specialty polymers.
• Cosmetic & Personal Care Actives: Potential intermediate for the development of next-generation polyhydroxy acid (PHA)-based skincare ingredients known for gentle exfoliation and moisturization.
• Agrochemical Development: Employed in the research and synthesis of novel, biologically active compounds for crop protection.
• Food & Flavor Chemistry: Can be utilized as an intermediate in the production of certain food additives or flavor enhancers with specific isomeric purity.

Basic Information

Product Name	(2S,4S,5R)-2,4,5,6-Tetrahydroxyhexanoic Acid
CAS No.	29625-79-4
Molecular Formula	C6H12O6
Molecular Weight	180.16 g/mol
Synonyms	(2S,4S,5R)-2,4,5,6-Tetrahydroxycaproic Acid; L-Gulonic Acid; (2S,4S,5R)-Tetrahydroxyhexanoic Acid; L-(+)-Gulonic Acid; (S,S,R)-Tetrahydroxyhexanoic Acid; 2,4,5,6-Tetrahydroxy-L-hexanoic Acid; Vitamin C Metabolite Intermediate
EINECS	Contact for details

Quality Control

Our (2S,4S,5R)-2,4,5,6-Tetrahydroxyhexanoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.