Description

13(S)-Hydroxyoctadeca-9Z,11E-Dienoic Acid is a high-purity, stereospecific hydroxy fatty acid derivative, also known as 13(S)-HODE. This compound serves as a critical biochemical intermediate and reference standard in lipidomics and metabolic pathway research. It is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced chemical synthesis sectors who require precise, well-characterized bioactive lipids for development and quality control.

Application

• Biochemical Research: Used as a key reference standard and analytical marker in the study of lipoxygenase pathways, inflammation, and cell signaling.
• Pharmaceutical Development: Serves as a critical intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel therapeutics targeting metabolic disorders.
• Nutraceuticals & Cosmeceuticals: Incorporated into advanced formulations for its potential bioactive properties, requiring high-purity, well-defined ingredients.
• Analytical Chemistry: Employed as a certified standard for HPLC, GC-MS, and LC-MS methods to quantify lipid peroxidation products and eicosanoids in biological samples.
• Cell Culture & In Vitro Studies: Applied in controlled experiments to investigate the effects of specific oxylipins on cellular function and metabolism.
• Chemical Synthesis: Acts as a chiral building block for the synthesis of more complex, stereochemically defined lipid mediators and analogs.

Basic Information

Product Name	13(S)-Hydroxyoctadeca-9Z,11E-Dienoic Acid
CAS No.	29623-28-7
Molecular Formula	C₁₈H₃₂O₃
Molecular Weight	296.45 g/mol
Synonyms	13(S)-HODE; (13S)-13-Hydroxy-9Z,11E-octadecadienoic Acid; 13S-HODE; 13(S)-Hydroxy-9-cis,11-trans-octadecadienoic Acid; 13S-Hydroxyoctadecadienoic Acid; 13(S)-Hydroxy Linoleic Acid; 13(S)-HOTrE; Coriolic Acid (stereoisomer)
EINECS	Contact for details

Quality Control

Every batch of 13(S)-Hydroxyoctadeca-9Z,11E-Dienoic Acid is produced and controlled under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, typically including chiral HPLC analysis to confirm the 13(S) configuration. Certificates of Analysis (COA) detailing purity (by HPLC), specific rotation, and impurity profiles are available for all shipments, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% 13(S) isomer
Specific Rotation	Contact for details
Solubility	Soluble in ethanol, DMSO, and strong acid/organic solvent mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.