Description

2-[Bis(2-Chloroethoxy)Phosphoryl]-N,n-Bis(2-Chloroethyl)Ethanamine Hydrochloride is a specialized organophosphorus compound with a nitrogen mustard backbone, primarily utilized as a key intermediate in advanced chemical synthesis. Its molecular structure makes it a valuable precursor for the development of targeted pharmaceutical agents and sophisticated fine chemicals. This product is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and other targeted drug candidates.
• Agrochemical Synthesis: Used as a precursor for developing novel pesticides and herbicides with specific modes of action.
• Chemical Research: Serves as a versatile reagent in academic and industrial R&D for exploring new organophosphorus chemistry and creating functional molecules.
• Ligand and Chelator Precursor: Employed in the synthesis of complexing agents and ligands for metal catalysis or extraction processes.
• Polymer Modification: Acts as a reactive monomer or cross-linking agent for creating specialty polymers with specific functional properties.
• Bioconjugation Chemistry: Utilized in the development of linker molecules for antibody-drug conjugates (ADCs) and other biopharmaceutical constructs.

Basic Information

Product Name	2-[Bis(2-Chloroethoxy)Phosphoryl]-N,n-Bis(2-Chloroethyl)Ethanamine Hydrochloride
CAS No.	29619-90-7
Molecular Formula	C12H24Cl5N1O3P1
Molecular Weight	429.56 g/mol
Synonyms	N,N-Bis(2-chloroethyl)-2-[bis(2-chloroethoxy)phosphoryl]ethanamine hydrochloride; Tris(2-chloroethyl)amine phosphoramide mustard hydrochloride derivative; 2-[Bis(2-chloroethoxy)phosphinyl]-N,N-bis(2-chloroethyl)ethanamine hydrochloride; Phosphorodiamidic acid, P,P-bis(2-chloroethyl)-N-(2-chloroethyl)-, triester, hydrochloride; HN2 Phosphoramide Mustard Analog Hydrochloride; Cyclophosphamide Impurity/Intermediate; Nor-Nitrogen Mustard Phosphoramide Ester HCl
EINECS	Contact for details

Quality Control

Every batch of 2-[Bis(2-Chloroethoxy)Phosphoryl]-N,n-Bis(2-Chloroethyl)Ethanamine Hydrochloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for advanced chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and elemental analysis, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.