Description

3-o-Benzoyl-1,2:5,6-Bis(Di-o-Isopropylidene)-α-D-Allofuranose is a key protected carbohydrate intermediate, specifically a benzoylated and diacetonide-protected derivative of D-allofuranose. This compound is critically important for its role in the stereoselective synthesis of complex nucleosides, nucleotides, and other biologically active sugar derivatives. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and novel oligonucleotide therapeutics.

Application

• Nucleoside/Nucleotide Synthesis: A crucial chiral building block for the preparation of modified nucleosides with potential antiviral and antitumor activity.
• Oligonucleotide Chemistry: Used in the synthesis of sugar-modified oligonucleotides for antisense, siRNA, and diagnostic applications.
• Pharmaceutical Intermediates: Serves as a protected precursor in multi-step synthetic routes for active pharmaceutical ingredients (APIs).
• Glycochemistry Research: Employed in academic and industrial research to explore new glycosylation methodologies and carbohydrate-based drug candidates.
• Chemical Biology Probes: Acts as a starting material for synthesizing labeled or functionalized sugars used to study biological processes.

Basic Information

Item	Details
Product Name	3-o-Benzoyl-1,2:5,6-Bis(Di-o-Isopropylidene)-α-D-Allofuranose
CAS No.	29474-73-5
Molecular Formula	C23H30O7
Molecular Weight	418.48 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-3-O-benzoyl-α-D-allofuranose; 3-O-Benzoyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose; 3-O-Benzoyl-1,2:5,6-di-O-(1-methylethylidene)-α-D-allofuranose; α-D-Allofuranose, 3-benzoyl-1,2:5,6-bis-O-(1-methylethylidene)-; 3-O-Benzoyl-di-O-isopropylidene-α-D-allofuranose; D-Allofuranose, 3-benzoyl-1,2:5,6-bis-O-(1-methylethylidene)-
EINECS	Contact for details

Quality Control

Our 3-o-Benzoyl-1,2:5,6-Bis(Di-o-Isopropylidene)-α-D-Allofuranose is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Specified range
Specific Rotation	Specified range
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.