Description

Droclidinium CAS NO 29125-56-2 is a quaternary ammonium compound belonging to the anticholinergic class of pharmaceuticals. It is valued for its potent antimuscarinic activity, which makes it a key intermediate in the synthesis of specialized active pharmaceutical ingredients (APIs). This compound is primarily required by pharmaceutical manufacturers and advanced research institutions developing treatments for conditions involving smooth muscle spasms, such as gastrointestinal and urinary disorders.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of anticholinergic and antispasmodic drug substances.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the manufacturing process of finished dosage forms targeting muscarinic receptors.
• Research & Development: Serves as a reference standard and a key starting material in pharmacological studies for new therapeutic agents.
• Gastrointestinal Drug Production: Incorporated into the development of medications for treating peptic ulcers, irritable bowel syndrome (IBS), and other GI motility disorders.
• Urological Drug Formulation: Utilized in creating APIs for drugs that manage overactive bladder and urinary incontinence.
• Chemical Synthesis: Acts as a versatile quaternary ammonium salt in various organic synthesis pathways within fine chemical production.

Basic Information

Product Name	Droclidinium
CAS No.	29125-56-2
Molecular Formula	C22H28BrNO3
Molecular Weight	434.37 g/mol
Synonyms	Droclidinium Bromide; 3-Hydroxy-1-methylquinuclidinium Bromide Benzilate; (3-Hydroxy-1-methylquinuclidinium) benzilate bromide; Quinuclidin-3-ol, 1-methyl-, benzilate bromide (1:1); Benzilic acid 3-hydroxy-1-methylquinuclidinium bromide ester; Ro 2-3773; CAS 29125-56-2
EINECS	Contact for details

Quality Control

Our Droclidinium is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Quality is verified through comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to cGMP standards where applicable to support our global clientele in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.