Description

2H-1,3,2-Oxazaphosphorine, 2-(1-Aziridinyl)-3-(2-Chloroethyl)Tetrahydro-, 2-Oxide is a specialized heterocyclic organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its unique molecular architecture, featuring both aziridine and chloroethyl functional groups, makes it a valuable precursor for constructing complex molecules with targeted biological or material properties. This compound is primarily sought by research institutions and pharmaceutical developers for applications in medicinal chemistry and as a building block for novel polymer systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of experimental chemotherapeutic agents and targeted drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel bioactive molecules in drug discovery programs.
• Polymer Science: Serves as a functional monomer or cross-linking agent in the development of specialty polymers and resins.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological mechanisms.
• Agrochemical Development: Potential intermediate in the research and development of new crop protection agents.
• Academic & Industrial R&D: Fundamental building block for exploratory synthesis in organic and organometallic chemistry.

Basic Information

Product Name	2H-1,3,2-Oxazaphosphorine, 2-(1-Aziridinyl)-3-(2-Chloroethyl)Tetrahydro-, 2-Oxide
CAS No.	29102-47-4
Molecular Formula	C6H12ClN2O2P
Molecular Weight	210.60 g/mol
Synonyms	2-(1-Aziridinyl)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-Oxide; Cyclophosphamide Impurity; 1-Aziridineethanol, 2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide derivative; NSC 26271; Ifosfamide Related Compound; Aziridine Oxazaphosphorine Derivative; Phosphoramide Mustard Precursor
EINECS	Contact for details

Quality Control

Our production of 2H-1,3,2-Oxazaphosphorine, 2-(1-Aziridinyl)-3-(2-Chloroethyl)Tetrahydro-, 2-Oxide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing specific batch results are provided to guarantee full traceability and compliance with your internal quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.