Description

Prednimustine is a synthetic corticosteroid esterified with chlorambucil, combining anti-inflammatory and alkylating properties. This unique molecular design makes it a compound of significant interest for advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of oncology and immunology. Prednimustine CAS NO 29069-24-7 represents a specialized chemical for targeted applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of specialized corticosteroid-based active pharmaceutical ingredients (APIs).
• Oncology Research: Used as a reference standard or experimental compound in preclinical studies investigating combination chemotherapeutic agents.
• Biochemical Research: Employed in studies exploring the mechanisms of steroid-alkylator hybrid molecules and their cellular interactions.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Drug Discovery Programs: Utilized in screening libraries for identifying new drug candidates with dual anti-inflammatory and cytotoxic activity.

Basic Information

Product Name	Prednimustine
CAS No.	29069-24-7
Molecular Formula	C31H39Cl2NO6
Molecular Weight	592.55 g/mol
Synonyms	Sterecyt; Leo 1031; NSC-134087; Prednimustinum; 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-[4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate]; Prednisolone 21-[4-[p-[bis(2-chloroethyl)amino]phenyl]butyrate]; Chlorambucil prednisolone ester
EINECS	Contact for details

Quality Control

Our Prednimustine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.