Description

Trifluoroethylamine is a versatile fluorinated amine building block, essential for introducing the trifluoroethyl group into complex molecular architectures. Its unique combination of high electronegativity and lipophilicity makes it a critical intermediate for enhancing the biological activity and metabolic stability of target compounds. This chemical is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing advanced products.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic display technologies.
• Polymer Modification: Imparts unique surface properties, chemical resistance, and stability when incorporated into specialty polymers and coatings.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and reductive amination reactions to introduce the 2,2,2-trifluoroethylamine moiety.
• Fluorinated Surfactant Precursor: Used in the synthesis of surfactants with superior wetting and leveling properties for demanding industrial applications.

Basic Information

Product Name	Trifluoroethylamine
CAS No.	29010-16-0
Molecular Formula	C2H4F3N
Molecular Weight	99.05 g/mol
Synonyms	2,2,2-Trifluoroethylamine; 2,2,2-Trifluoroethanamine; 1-Amino-2,2,2-trifluoroethane; Trifluoroethylamine Hydrochloride (salt form); TFEA; α,α,α-Trifluoroethylamine; Perfluoroethylamine (common misnomer); UN 2739 (for amine liquids, n.o.s.)
EINECS	249-363-5

Quality Control

Our Trifluoroethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Density (at 20°C)	1.25 - 1.30 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.