Description

(Fluoromethyl)Trimethylsilane is a highly versatile organosilicon reagent featuring a reactive fluoromethyl group. This compound is valued for its role as a key building block in organic synthesis, particularly for introducing fluoromethyl functionality into target molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel fluorinated compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of fluorinated active pharmaceutical ingredients (APIs), where the fluorine atom can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides, leveraging fluorine's ability to enhance biological activity and environmental persistence.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier in the production of specialty silicones and fluoropolymers, imparting unique surface properties and chemical resistance.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and cross-coupling reactions to incorporate the -CH2F moiety into complex organic frameworks.
• Liquid Crystal & Electronic Chemicals: Used in the synthesis of fluorinated liquid crystals and semiconductor precursors for display and microelectronics industries.
• Radiotracer & Diagnostic Agent Precursor: Acts as a starting material for synthesizing 18F-labeled compounds used in Positron Emission Tomography (PET) imaging.

Basic Information

Product Name	(Fluoromethyl)Trimethylsilane
CAS No.	28871-61-6
Molecular Formula	C4H11FSi
Molecular Weight	106.21 g/mol
Synonyms	Trimethyl(fluoromethyl)silane; Fluoromethyltrimethylsilane; (Fluoromethyl)trimethylsilicon; (Fluoromethyl)trimethylsilane; (Fluoromethyl)trimethylsilane; (Fluoromethyl)trimethylsilane; (Fluoromethyl)trimethylsilane; (Fluoromethyl)trimethylsilane
EINECS	Contact for details

Quality Control

Our (Fluoromethyl)Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.