Description

2,2-Dibromo-2-(Diethoxyphosphinyl)Acetic Acid Ethyl Ester is a specialized organophosphorus compound that serves as a versatile synthetic intermediate. Its unique structure, featuring both bromine and phosphonate functional groups, makes it a valuable building block for constructing complex molecules in advanced chemical synthesis. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring phosphonate or α-bromo ester moieties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, pesticides, and plant growth regulators.
• Organophosphorus Chemistry: Serves as a critical reagent in Horner-Wadsworth-Emmons (HWE) olefination reactions and other carbon-carbon bond forming processes.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Useful for synthesizing activity-based probes or inhibitors targeting enzymes that interact with phosphonate esters.
• Academic & Industrial R&D: Employed in methodological studies and scale-up process development for complex organic molecules.

Basic Information

Product Name	2,2-Dibromo-2-(Diethoxyphosphinyl)Acetic Acid Ethyl Ester
CAS No.	28845-75-2
Molecular Formula	C8H15Br2O5P
Molecular Weight	382.00 g/mol
Synonyms	Ethyl 2,2-Dibromo-2-(diethoxyphosphinyl)acetate; Diethyl (2,2-Dibromo-2-ethoxy-2-oxoethyl)phosphonate; (Diethoxyphosphinyl)dibromoacetic Acid Ethyl Ester; Acetic acid, 2,2-dibromo-2-(diethoxyphosphinyl)-, ethyl ester; Ethyl (Diethoxyphosphoryl)dibromoacetate; DBDAE; Dibromophosphonoacetate Ethyl Ester
EINECS	Contact for details

Quality Control

Our 2,2-Dibromo-2-(Diethoxyphosphinyl)Acetic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its sensitivity, the container should be kept tightly sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.