Description

Estra-1,3,5(10)-Triene-3,17-Diol (17Beta)-, Hydrogen Sulfate is a specific, high-purity sulfate ester derivative of estradiol. This compound is a critical pharmaceutical intermediate and reference standard used in the development and quality control of steroidal drugs and hormone-based therapies. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, well-characterized building blocks for advanced synthesis and analytical applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of steroidal active pharmaceutical ingredients (APIs) and conjugated estrogens.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical laboratories to ensure product purity and compliance.
• Biochemical Research: Employed in life science research to study estrogen metabolism, receptor interactions, and the synthesis of hormone derivatives.
• Veterinary Medicine: Utilized in the formulation of hormone treatments and fertility management solutions for animals.
• Diagnostic Reagents: Serves as a component in the manufacture of calibration standards and reagents for clinical diagnostic assays.

Basic Information

Product Name	Estra-1,3,5(10)-Triene-3,17-Diol (17Beta)-, Hydrogen Sulfate
CAS No.	28814-94-0
Molecular Formula	C18H24O5S
Molecular Weight	352.45 g/mol
Synonyms	Estradiol 3-Sulfate; 17β-Estradiol 3-Sulfate; Estra-1,3,5(10)-triene-3,17β-diol 3-sulfate; E2-3S; Estradiol 3-monosulfate; 3-Hydroxyestra-1,3,5(10)-trien-17β-yl hydrogen sulfate; NSC 49109
EINECS	Contact for details

Quality Control

Our Estra-1,3,5(10)-Triene-3,17-Diol (17Beta)-, Hydrogen Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets stringent specifications for pharmaceutical-grade intermediates. Certificates of Analysis (COA) documenting all test results are provided to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.