Description

Tetrahydro-3-(Isocyanatomethyl)Thiophene 1,1-Dioxide is a specialized, highly reactive isocyanate derivative used as a key building block in advanced polymer synthesis. Its core value lies in introducing a sulfone-functionalized, saturated heterocyclic structure into polymer backbones, enhancing thermal stability and chemical resistance. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and high-performance materials sectors, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for sulfone-containing drug candidates.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that require the unique properties of the sulfolane-derived moiety.
• Polymer & Resin Modification: Acts as a reactive monomer for producing polyurethanes, polyureas, and other specialty polymers with enhanced thermal and hydrolytic stability.
• Crosslinking Agent: Employed in coatings, adhesives, and elastomers to create dense, high-performance crosslinked networks.
• Material Science R&D: A valuable reagent for developing new high-temperature polymers, engineering plastics, and advanced composite materials.
• Chemical Synthesis Reagent: Utilized in organic synthesis to introduce the tetrahydrothiophene-1,1-dioxide (sulfolane) scaffold into more complex molecules.

Basic Information

Product Name	Tetrahydro-3-(Isocyanatomethyl)Thiophene 1,1-Dioxide
CAS No.	28800-41-1
Molecular Formula	C6H9NO3S
Molecular Weight	175.21 g/mol
Synonyms	3-(Isocyanatomethyl)tetrahydrothiophene 1,1-dioxide; Tetrahydro-3-(isocyanatomethyl)thiophene sulfone; 3-Isocyanatomethylsulfolane; Sulfolane-3-methyl isocyanate; 1,1-Dioxotetrahydro-3-thiophenemethyl isocyanate; 3-(Isocyanatomethyl)sulfolane; Isocyanatomethylsulfolane
EINECS	Contact for details

Quality Control

Our Tetrahydro-3-(Isocyanatomethyl)Thiophene 1,1-Dioxide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to minimize degradation and polymerization. Due to its highly volatile and reactive isocyanate nature, containers must be kept tightly sealed under a dry inert atmosphere (e.g., nitrogen or argon) to exclude moisture. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Isocyanate Content (Titration)	Contact for details
Specific Gravity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.