Description

Menitrazepam is a synthetic benzodiazepine derivative, a class of compounds known for their central nervous system activity. This high-purity compound is critical for pharmaceutical research and development, particularly in the study of receptor pharmacology and the synthesis of novel therapeutic agents. It serves as a key intermediate or reference standard for researchers and manufacturers in the global pharmaceutical, biotechnology, and analytical chemistry sectors.

Application

• Pharmaceutical Research & Development: Used as a reference standard or active pharmaceutical ingredient (API) intermediate in the development of central nervous system (CNS) targeting drugs.
• Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for method development, validation, and quality control testing in HPLC, GC-MS, and other analytical techniques.
• Biochemical Research: Employed in preclinical studies to investigate the mechanism of action, metabolism, and structure-activity relationships (SAR) of benzodiazepines.
• Chemical Synthesis: Acts as a crucial building block or precursor in the multi-step synthesis of more complex benzodiazepine analogues and related compounds.

Basic Information

Product Name	Menitrazepam
CAS No.	28781-64-8
Molecular Formula	C₁₆H₁₃ClN₂O₂
Molecular Weight	300.74 g/mol
Synonyms	Menitrazepam; 7-Chloro-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1-Methyl-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Ro 07-9749; Ro 07 9749; Ro-07-9749; 1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-
EINECS	Contact for details

Quality Control

Our Menitrazepam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research-grade materials. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.