Description

Pyrrolo(1,2,3-Ef)(1,5)Benzodiazepine, 1,2,3,4,6,7-Hexahydro-9-Chloro-2-Phenyl-, Monohydrochloride is a complex, heterocyclic organic compound belonging to the benzodiazepine class, offered as a high-purity monohydrochloride salt. This compound is of significant interest for its potential as a key pharmaceutical intermediate or a scaffold for advanced research in medicinal chemistry and drug discovery. It is primarily utilized by R&D laboratories and chemical synthesis units within the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Biochemical Research: Potential application as a ligand or probe in studying receptor interactions within neurological and pharmacological research.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Organic Synthesis: Employed in advanced synthetic organic chemistry for constructing complex polycyclic molecular architectures.

Basic Information

Item	Detail
Product Name	Pyrrolo(1,2,3-Ef)(1,5)Benzodiazepine, 1,2,3,4,6,7-Hexahydro-9-Chloro-2-Phenyl-, Monohydrochloride
CAS No.	28740-99-0
Molecular Formula	C18H18ClN3·HCl
Molecular Weight	348.27 g/mol
Synonyms	9-Chloro-2-phenyl-1,2,3,4,6,7-hexahydropyrrolo[1,2,3-ef][1,5]benzodiazepine monohydrochloride; 1,2,3,4,6,7-Hexahydro-9-chloro-2-phenylpyrrolo[1,2,3-ef][1,5]benzodiazepine hydrochloride; Pyrrolobenzodiazepine HCl derivative; PBD Monohydrochloride Intermediate
EINECS	Contact for details

Quality Control

Our Pyrrolobenzodiazepine Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.