Description

Benzeneacetic Acid, α-Methyl-, Methyl Ester, (αs)- CAS NO 28645-07-0 is a high-purity chiral ester derivative of phenylacetic acid, serving as a critical synthetic intermediate and building block in advanced organic synthesis. Its defined stereochemistry and ester functionality make it a valuable precursor for constructing complex molecules with specific spatial orientations. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), analgesics, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the specific stereochemistry influences biological activity.
• Flavor and Fragrance Industry: Serves as a precursor for synthetic aromatic compounds, contributing to complex scent and flavor profiles.
• Organic Synthesis Research: A versatile reagent for academic and industrial R&D, particularly in methodologies involving esterification, chiral resolution, and asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including liquid crystals, dyes, and polymer additives.

Basic Information

Product Name	Benzeneacetic Acid, α-Methyl-, Methyl Ester, (αs)-
CAS No.	28645-07-0
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(S)-(-)-Methyl 2-Phenylpropionate; (S)-Methyl 2-Phenylpropanoate; (S)-α-Methylbenzeneacetic Acid Methyl Ester; L-Methyl Hydratropate; Methyl (S)-2-Phenylpropionate; (S)-2-Phenylpropionic Acid Methyl Ester; (αS)-α-Methylbenzenecetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, α-Methyl-, Methyl Ester, (αs)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]D20	Contact for details
Refractive Index nD20	Contact for details
Density (g/mL at 20°C)	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.