Description

(1R,4S,5R)-1,8-Dimethyl-4-(1-Methylethenyl)Spiro[4.5]Dec-7-Ene is a high-purity, chiral spirocyclic terpene derivative with a complex molecular architecture. This compound matters as a valuable and versatile chiral building block and intermediate for advanced organic synthesis, particularly in the development of fine chemicals and active pharmaceutical ingredients (APIs). It is needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fragrance industries seeking to introduce specific stereochemistry and structural complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, especially those requiring specific stereocenters and rigid spirocyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where its unique structure can contribute to biological activity.
• Fragrance & Flavor Chemistry: Serves as a precursor for the synthesis of novel aroma chemicals and terpene-based fragrance ingredients.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs and novel molecular architectures.
• Catalyst & Ligand Development: Potential precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers with unique thermal or optical properties.

Basic Information

Product Name	(1R,4S,5R)-1,8-Dimethyl-4-(1-Methylethenyl)Spiro[4.5]Dec-7-Ene
CAS No.	28477-64-7
Molecular Formula	C14H22
Molecular Weight	190.32 g/mol
Synonyms	(-)-β-Vetispirene; (1R,4S,5R)-1,8-Dimethyl-4-isopropenylspiro[4.5]dec-7-ene; β-Vetispirene; Vetispirene; Spiro[4.5]dec-7-ene, 1,8-dimethyl-4-(1-methylethenyl)-, (1R,4S,5R)-; 1,8-Dimethyl-4-isopropenylspiro[4.5]dec-7-ene; (1R,4S,5R)-1,8-Dimethyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-ene
EINECS	Contact for details

Quality Control

Our (1R,4S,5R)-1,8-Dimethyl-4-(1-Methylethenyl)Spiro[4.5]Dec-7-Ene is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC/HPLC)	≥ 95.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.