Description

2-Toluoyl Choline is a specialized organic salt with significant utility in biochemical and pharmaceutical research. Its primary value lies in its role as a potent and selective inhibitor of butyrylcholinesterase, an enzyme of interest in the study of neurodegenerative conditions. This makes it a critical research chemical for academic institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on neurological pathways and enzyme kinetics.

Application

• Biochemical Research: Used as a selective inhibitor of butyrylcholinesterase (BChE) in enzymatic studies and kinetic assays.
• Pharmaceutical Development: Serves as a key reference standard and tool compound in drug discovery programs targeting Alzheimer's disease and other cognitive disorders.
• Diagnostic Reagents: Incorporated into in vitro diagnostic kits for the quantitative measurement of cholinesterase activity in clinical samples.
• Neuroscience Studies: Employed to investigate the cholinergic system and the distinct physiological roles of acetylcholinesterase vs. butyrylcholinesterase.
• Toxicology Screening: Utilized in assays to assess the effect of various compounds on cholinesterase activity, relevant to environmental and industrial toxicology.

Basic Information

Product Name	2-Toluoyl Choline
CAS No.	28418-91-9
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	o-Toluoylcholine; 2-Methylbenzoylcholine; (2-Methylbenzoyl)choline; Butyrylcholinesterase Inhibitor; BChE Inhibitor; Choline 2-methylbenzoate; 2-Toluoylcholine iodide (salt form reference)
EINECS	Contact for details

Quality Control

Our 2-Toluoyl Choline is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.