Description

4-Chloro-2-Phenoxypyridine is a versatile halogenated pyridine derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a chloro substituent and a phenoxy group, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the pyridine core is a common pharmacophore.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination for constructing biaryl systems.
• Ligand Preparation: Utilized for the preparation of nitrogen-containing ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	4-Chloro-2-Phenoxypyridine
CAS No.	28373-64-0
Molecular Formula	C11H8ClNO
Molecular Weight	205.64 g/mol
Synonyms	2-Phenoxy-4-chloropyridine; 4-Chloro-2-phenoxypyridine; 4-Chloro-2-phenoxy-pyridine; 4-Chloro-2-(phenoxy)pyridine; Pyridine, 4-chloro-2-phenoxy-; 28373-64-0; 4-Chloro-2-phenoxypyridine (9CI)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Phenoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.