Description

4-(2-Bromoacetyl)-2,6-Dimethoxyphenyl Acetate is a specialized brominated aromatic ester intermediate of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a reactive bromoacetyl group and protected phenolic functionalities, makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other small molecule therapeutics.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, or plant growth regulators, leveraging its reactive sites for structural diversification.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex dyes, pigments, and advanced organic materials requiring specific brominated aromatic motifs.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological processes due to its ability to undergo selective coupling reactions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including studies on cross-coupling reactions and heterocycle formation.

Basic Information

Product Name	4-(2-Bromoacetyl)-2,6-Dimethoxyphenyl Acetate
CAS No.	28294-48-6
Molecular Formula	C12H13BrO5
Molecular Weight	317.13 g/mol
Synonyms	2,6-Dimethoxyphenyl 2-Bromoacetate 4-Acetate; 1-(4-Acetoxy-3,5-dimethoxyphenyl)-2-bromoethanone; 2-Bromo-1-(4-acetoxy-3,5-dimethoxyphenyl)ethanone; 4-Acetoxy-3,5-dimethoxy-α-bromoacetophenone; 4-Acetoxy-3,5-dimethoxyphenacyl bromide; Ethanone, 2-bromo-1-[4-(acetyloxy)-3,5-dimethoxyphenyl]-; 4-(Bromoacetyl)-2,6-dimethoxyphenyl acetate
EINECS	Contact for details

Quality Control

Our 4-(2-Bromoacetyl)-2,6-Dimethoxyphenyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.