Description

(4R)-4β,5α-Dimethyl-6α-[1-Methyl-1-(Trimethylsiloxy)Ethyl]-2,3,4,4A,5,6,7,8-Octahydronaphthalene is a high-purity, organosilicon-functionalized octahydronaphthalene derivative, serving as a critical chiral intermediate in advanced organic synthesis. Its value lies in the precise stereochemistry and the reactive trimethylsiloxy group, which enable its use in constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex drug candidates, especially in steroid and terpene-related therapeutic areas.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in catalytic asymmetric reactions to induce specific stereochemistry in target molecules.
• Fine Chemical Production: Serves as a specialized intermediate in the manufacture of high-value agrochemicals, flavors, and fragrances.
• Material Science Research: Investigated for incorporation into novel organic frameworks or silicon-containing polymers with tailored properties.
• Process Chemistry Development: Used in route scouting and optimization for scalable production of complex organic compounds.

Basic Information

Item	Details
Product Name	(4R)-4β,5α-Dimethyl-6α-[1-Methyl-1-(Trimethylsiloxy)Ethyl]-2,3,4,4A,5,6,7,8-Octahydronaphthalene
CAS No.	28272-09-5
Molecular Formula	C19H36OSi
Molecular Weight	308.58 g/mol
Synonyms	(4R)-4β,5α-Dimethyl-6α-[1-methyl-1-(trimethylsiloxy)ethyl]decahydronaphthalene; 4β,5α-Dimethyl-6α-[1-methyl-1-(trimethylsiloxy)ethyl]-2,3,4,4a,5,6,7,8-octahydronaphthalene; (4R)-4β,5α-Dimethyl-6α-[1-methyl-1-(trimethylsiloxy)ethyl]perhydronaphthalene; Silane, [[(4R)-4β,5α-dimethyl-6α-(1-methyl-1-hydroxyethyl)decahydronaphthalen-2-yl]oxy]trimethyl-; Trimethyl[[(4R)-4β,5α-dimethyl-6α-(1-methyl-1-hydroxyethyl)decahydronaphthalen-2-yl]oxy]silane
EINECS	Contact for details

Quality Control

Our (4R)-4β,5α-Dimethyl-6α-[1-Methyl-1-(Trimethylsiloxy)Ethyl]-2,3,4,4A,5,6,7,8-Octahydronaphthalene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate to maximize shelf-life. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.