Description

4-Fluoro-3-Nitrophenyl Azide is a versatile aryl azide compound, a key intermediate in photoaffinity labeling and click chemistry applications. Its value lies in its ability to form covalent bonds upon photolysis, making it indispensable for probing biomolecular interactions and synthesizing complex molecular architectures. This product is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new drugs, advanced polymers, and functionalized surfaces.

Application

• Photoaffinity Labeling Probes: A critical reagent for identifying and studying protein-ligand interactions, receptor binding sites, and enzyme active sites in drug discovery.
• Click Chemistry Synthesis: Serves as a key building block for Huisgen 1,3-dipolar cycloaddition reactions to create triazole-linked bioconjugates and polymers.
• Surface Functionalization: Used to modify and covalently attach specific functional groups to polymers, nanoparticles, and biosensor surfaces.
• Pharmaceutical Intermediate: An important synthon in the multi-step synthesis of fluorinated and nitrogen-containing active pharmaceutical ingredients (APIs).
• Agrochemical Research: Employed in the development of novel herbicides and pesticides through targeted molecular design.
• Crosslinking Agent: Facilitates the crosslinking of polymer chains under UV light to create materials with tailored mechanical properties.
• Bioconjugation: Enables the stable attachment of dyes, tags, or drugs to antibodies, peptides, and other biomolecules for diagnostics and therapeutics.
• Material Science Research: Used in the creation of advanced functional materials, including self-assembled monolayers and smart coatings.

Basic Information

Product Name	4-Fluoro-3-Nitrophenyl Azide
CAS No.	28166-06-5
Molecular Formula	C6H3FN4O2
Molecular Weight	182.11 g/mol
Synonyms	1-Azido-4-fluoro-3-nitrobenzene; 4-Fluoro-3-nitro-1-azidobenzene; 3-Nitro-4-fluorophenyl azide; (4-Fluoro-3-nitrophenyl)azide; p-Fluoro-m-nitrophenyl azide; Azidobenzene, 4-fluoro-3-nitro-; 4-Fluoro-3-nitrobenzene azide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Nitrophenyl Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C/59-77°F). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.