Description

(E)-1-(2,4-Dihydroxy-5-Methoxyphenyl)-3-Phenyl-2-Propen-1-One is a high-purity chalcone derivative, a key structural motif in organic synthesis and pharmaceutical research. This compound is valued for its role as a versatile synthetic intermediate and a potential bioactive scaffold in drug discovery programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for synthesizing novel drug candidates, particularly those targeting inflammation, cancer, and microbial infections.
• Organic Synthesis Reagent: Used in various organic transformations, including cyclization reactions, to create complex heterocyclic compounds.
• Agrochemical Research: Acts as a precursor in developing new pesticides and herbicides due to its bioactive chalcone core.
• Material Science: Investigated for use in organic electronic materials and as a component in advanced polymer synthesis.
• Biochemical Research: Employed as a standard or probe in studying enzyme inhibition and biological pathway mechanisms.
• Flavor & Fragrance Industry: Potential use in synthesizing complex aromatic molecules for specialty applications.

Basic Information

Product Name	(E)-1-(2,4-Dihydroxy-5-Methoxyphenyl)-3-Phenyl-2-Propen-1-One
CAS No.	28143-82-0
Molecular Formula	C₁₆H₁₄O₄
Molecular Weight	270.28 g/mol
Synonyms	2',4'-Dihydroxy-5'-methoxychalcone; 1-(2,4-Dihydroxy-5-methoxyphenyl)-3-phenyl-2-propen-1-one; 5'-Methoxy-2',4'-dihydroxychalcone; (E)-2',4'-Dihydroxy-5'-methoxychalcone; NSC 407296; Chalcone derivative 28143-82-0; Light yellow crystalline powder (E)-isomer
EINECS	Contact for details

Quality Control

Our (E)-1-(2,4-Dihydroxy-5-Methoxyphenyl)-3-Phenyl-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.