Description

Spiro[3.3]heptane-3-carboxylic acid is a high-purity, synthetically valuable bicyclic carboxylic acid building block. This compound is prized for its unique, rigid spirocyclic scaffold, which imparts desirable conformational and steric properties in advanced molecular design. It serves as a critical intermediate for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, enabling the development of novel active ingredients and functional molecules with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its stable three-dimensional structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Incorporated into polymers and advanced organic frameworks to modify thermal stability, rigidity, and optical properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors to study enzyme function and biological pathways.
• Flavor and Fragrance Chemistry: Acts as an intermediate for synthesizing complex aroma chemicals with unique olfactory profiles.

Basic Information

Product Name	Spiro[3.3]heptane-3-carboxylic Acid
CAS No.	28114-87-6
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	Spiro[3.3]heptane-3-carboxylic acid; 3-Spiro[3.3]heptanecarboxylic acid; Bicyclo[3.1.1]heptane-3-carboxylic acid, 6,6-dimethyl- (related structure); 3-Carboxyspiro[3.3]heptane; Spiroheptane-3-carboxylic acid
EINECS	Contact for details

Quality Control

We supply Spiro[3.3]heptane-3-carboxylic acid in high-purity grades suitable for research and scale-up applications. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Comprehensive analytical data, including HPLC purity and chiral purity where applicable, is documented. Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.