Description

4-(Dimethylamino)-4'-Fluorochalcone is a specialized fluorinated chalcone derivative, a key structural motif in organic synthesis and materials science. This compound matters for its role as a versatile building block in the development of advanced functional materials and biologically active molecules. It is needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and organic electronics industries for creating novel compounds with tailored optical and electronic properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and neurological disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chalcone core for bioactive molecule design.
• Organic Electronics: Acts as a building block for organic semiconductors, light-emitting diodes (OLEDs), and non-linear optical (NLO) materials due to its extended π-conjugation and donor-acceptor structure.
• Fluorescent Probe Synthesis: Employed in creating sensitive chemical sensors and bio-imaging agents, where the fluorochalcone structure provides a tunable fluorophore.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cyclization reactions and cross-coupling protocols.
• Material Science: Investigated for use in photonic crystals and as a component in advanced polymeric materials with specific light-absorption characteristics.

Basic Information

Product Name	4-(Dimethylamino)-4'-Fluorochalcone
CAS No.	28081-19-8
Molecular Formula	C₁₉H₁₈FNO
Molecular Weight	295.35 g/mol
Synonyms	4'-Fluoro-4-(dimethylamino)chalcone; (E)-1-(4-Fluorophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one; 4-Dimethylamino-4'-fluorochalcone; 4-Fluoro-4'-dimethylaminochalcone; 28081-19-8; 4-(N,N-Dimethylamino)-4'-fluorochalcone; p-Fluorophenyl 4-dimethylaminostyryl ketone; (E)-3-(4-(Dimethylamino)phenyl)-1-(4-fluorophenyl)prop-2-en-1-one
EINECS	Contact for details

Quality Control

Our 4-(Dimethylamino)-4'-Fluorochalcone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.