Description

3-Nitro-4'-Fluorochalcone (CAS NO 28081-18-7) is a high-purity, synthetically derived chalcone derivative characterized by its distinct nitro and fluoro substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile organic building block for complex chemical synthesis. It is essential for research and development in medicinal chemistry, particularly for organizations focused on creating novel therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and infectious diseases.
• Organic Synthesis Building Block: Utilized in heterocyclic chemistry for constructing complex molecular frameworks like pyrazolines and flavones.
• Material Science Research: Investigated for its potential in developing non-linear optical (NLO) materials and organic semiconductors due to its conjugated system.
• Biochemical Research: Used as a standard or probe in studying enzyme inhibition and biological activity-structure relationships (SAR).
• Agrochemical Development: Serves as an intermediate in the research and synthesis of new crop protection agents.
• Academic & Industrial R&D: A fundamental reagent for universities and corporate labs exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	3-Nitro-4'-Fluorochalcone
CAS No.	28081-18-7
Molecular Formula	C15H10FNO3
Molecular Weight	271.25 g/mol
Synonyms	(E)-1-(4-Fluorophenyl)-3-(3-nitrophenyl)prop-2-en-1-one; 3-Nitro-4'-fluorochalcone; 4'-Fluoro-3-nitrochalcone; 1-(4-Fluorobenzoyl)-3-(3-nitrophenyl)-2-propen-1-one; 2-Propen-1-one, 1-(4-fluorophenyl)-3-(3-nitrophenyl)-, (E)-; 3-Nitro-4'-fluorobenzalacetophenone; Chalcone, 3-nitro-4'-fluoro-
EINECS	Contact for details

Quality Control

Our 3-Nitro-4'-Fluorochalcone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.