Description

3,4-Dimethoxy-4'-Fluorochalcone CAS NO 28081-14-3 is a high-purity fluorinated chalcone derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a versatile synthetic intermediate and a promising scaffold for pharmaceutical research and development. It is primarily sought by R&D laboratories and chemical manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for synthesizing novel drug candidates, particularly in anti-inflammatory, anticancer, and antimicrobial research.
• Biochemical Research: Used as a reference standard or probe in studying biological pathways, enzyme inhibition, and structure-activity relationships (SAR).
• Agrochemical Development: Acts as a precursor in the synthesis of new active ingredients for crop protection products.
• Material Science: Investigated for its potential in creating organic electronic materials or nonlinear optical (NLO) materials due to its chalcone structure.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for exploratory chemistry and hit-to-lead optimization programs.

Basic Information

Product Name	3,4-Dimethoxy-4'-Fluorochalcone
CAS No.	28081-14-3
Molecular Formula	C₁₉H₁₉FO₃
Molecular Weight	314.35 g/mol
Synonyms	(E)-1-(4-Fluorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one; 4'-Fluoro-3,4-dimethoxychalcone; 1-(4-Fluorobenzoyl)-2-(3,4-dimethoxyphenyl)ethylene; 3,4-Dimethoxy-4'-fluorobenzalacetophenone; NSC 407347; Fluorochalcone derivative
EINECS	Contact for details

Quality Control

Our 3,4-Dimethoxy-4'-Fluorochalcone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive and easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.