Description

2-Chloro-4'-Fluorochalcone is a high-purity fluorinated chalcone derivative, a key structural motif in organic synthesis. This compound is valued for its role as a versatile synthetic intermediate and a promising scaffold in pharmaceutical research and development. It is primarily utilized by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly those targeting anti-inflammatory, anticancer, or antimicrobial pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chalcone core for bioactivity.
• Organic Synthesis: Acts as a key precursor for heterocyclic compounds, including flavones and pyrazolines, via cyclization reactions.
• Material Science: Investigated as an organic precursor for nonlinear optical (NLO) materials due to its conjugated π-system.
• Biochemical Tool Compound: Employed in academic and industrial research to study biological mechanisms and structure-activity relationships (SAR).
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Product Name	2-Chloro-4'-Fluorochalcone
CAS No.	28081-11-0
Molecular Formula	C₁₅H₁₀ClFO
Molecular Weight	260.69 g/mol
Synonyms	(E)-1-(2-Chlorophenyl)-3-(4-fluorophenyl)prop-2-en-1-one; 2-Chloro-4'-fluorochalcone; 1-(2-Chlorophenyl)-3-(4-fluorophenyl)-2-propen-1-one; 2'-Chloro-4-fluorochalcone; (2E)-1-(2-Chlorophenyl)-3-(4-fluorophenyl)prop-2-en-1-one; 2-Chloro-4'-fluorobenzalacetophenone; 4'-Fluoro-2-chlorochalcone
EINECS	Contact for details

Quality Control

Our 2-Chloro-4'-Fluorochalcone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.