Description

Diethyl-2-Ethoxycarbonylphenylphosphonate is a high-purity organophosphorus compound, specifically a phosphonate ester, valued for its role as a versatile synthetic intermediate. Its primary commercial significance lies in its application in the Wittig-Horner reaction, a key methodology for the stereoselective formation of carbon-carbon double bonds. This makes it an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize complex molecules, including active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of olefins via the Horner-Wadsworth-Emmons (HWE) reaction for producing drug candidates and APIs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific alkene geometries.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials.
• Fine Chemical Production: Serves as a precursor for synthesizing flavors, fragrances, and other high-value specialty chemicals.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Item	Details
Product Name	Diethyl-2-Ethoxycarbonylphenylphosphonate
CAS No.	28036-11-5
Molecular Formula	C14H21O5P
Molecular Weight	300.29 g/mol
Synonyms	Diethyl (2-Ethoxycarbonylphenyl)phosphonate; (2-Carbethoxyphenyl)phosphonic Acid Diethyl Ester; Diethyl 2-Carbethoxyphenylphosphonate; Phosphonic acid, P-(2-ethoxycarbonylphenyl)-, diethyl ester; Diethyl (o-ethoxycarbonylphenyl)phosphonate; Horner-Wadsworth-Emmons Reagent; HWE Reagent; Wittig-Horner Reagent
EINECS	Contact for details

Quality Control

Our Diethyl-2-Ethoxycarbonylphenylphosphonate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For customers with specific regulatory needs, we can support documentation for GMP, ISO, or REACH compliance upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.