Description

1,2,3-Tri-o-Acetyl-4,6-o-Ethylidene-β-D-Glucopyranose is a key protected carbohydrate intermediate, essential for the controlled synthesis of complex glycosides and nucleoside analogs. Its value lies in providing a stable, selectively reactive scaffold that enables precise chemical modifications in advanced organic synthesis. This compound is primarily needed by research institutions and pharmaceutical companies developing novel therapeutics, diagnostic agents, and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of nucleoside-based antiviral and anticancer drugs.
• Glycochemistry Research: Used in the study and development of novel glycosylation methodologies and carbohydrate-based probes.
• Oligosaccharide Synthesis: Serves as a protected glucose donor for the stepwise construction of complex carbohydrate chains.
• Prodrug Development: Employed to create masked or targeted forms of drug molecules to improve bioavailability or specificity.
• Chemical Biology: Utilized in the preparation of labeled sugars or molecular tools for studying biological processes.
• Fine Chemical Production: Acts as a chiral starting material for the manufacture of specialty chemicals and catalysts.

Basic Information

Product Name	1,2,3-Tri-o-Acetyl-4,6-o-Ethylidene-β-D-Glucopyranose
CAS No.	27994-30-5
Molecular Formula	C₁₅H₂₀O₉
Molecular Weight	344.31 g/mol
Synonyms	1,2,3-Tri-O-acetyl-4,6-O-ethylidene-β-D-glucopyranose; 4,6-O-Ethylidene-1,2,3-tri-O-acetyl-β-D-glucopyranose; Ethylidene Glucose Triacetate; β-D-Glucopyranose, 4,6-O-ethylidene-, 1,2,3-triacetate; 1,2,3-Triacetyl-4,6-ethylidene-β-D-glucopyranose; 4,6-Ethylidene-D-glucose triacetate; 1,2,3-Tri-O-acetyl-4,6-O-(1-methylethylidene)-β-D-glucopyranose (related isomer); Protected Glucose Triacetate
EINECS	Contact for details

Quality Control

Our 1,2,3-Tri-o-Acetyl-4,6-o-Ethylidene-β-D-Glucopyranose is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.