Description

1H-Tetrazole is a versatile five-membered heterocyclic compound containing four nitrogen atoms, serving as a critical building block and reagent in modern synthetic chemistry. Its primary value lies in its role as a precursor for tetrazolate salts, which are widely used as energetic materials and gas generators. This product is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for synthesizing active pharmaceutical ingredients (APIs) and creating photoactivatable crosslinkers.

Application

• Pharmaceutical Synthesis: Key intermediate in the production of cephalosporin and carbapenem antibiotics via 1,3-dipolar cycloaddition reactions.
• Agrochemical Manufacturing: Used as a core heterocycle in the synthesis of modern herbicides, fungicides, and plant growth regulators.
• Energetic Materials: Acts as a precursor for tetrazolate salts (e.g., lead styphnate alternatives) used in propellants, pyrotechnics, and gas generators for automotive airbags.
• Polymer Chemistry: Employed as a crosslinking agent and as a monomer for producing polymers with high nitrogen content and specific thermal properties.
• Peptide Synthesis & Bioconjugation: Utilized in click chemistry, particularly in Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for labeling and modifying biomolecules.
• Corrosion Inhibition: Serves as an effective corrosion inhibitor for metals in industrial cooling systems and other applications.
• Analytical Chemistry: Used as a derivatization agent in chromatography and as a reagent in various colorimetric detection methods.
• Material Science: Component in the development of metal-organic frameworks (MOFs) and other advanced functional materials.

Basic Information

Product Name	1H-Tetrazole
CAS No.	27988-97-2
Molecular Formula	CH2N4
Molecular Weight	70.05 g/mol
Synonyms	1H-Tetrazole; Tetrazole; Tetrazol; 1,2,3,4-Tetrazole; Pyrrodiazole; Tetrazacyclopentadiene; Aziminobenzene; H-Tetrazole; Tetrazolium base
EINECS	248-767-1

Quality Control

Our 1H-Tetrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and specialty chemical applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support compliance with global regulatory frameworks such as REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	156°C - 160°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.