Description

Dimethyl (Hydroxymethylene)Malonate is a versatile and highly reactive malonate derivative, serving as a critical building block in advanced organic synthesis. Its unique hydroxymethylene functionality makes it an invaluable reagent for constructing complex heterocyclic and pharmaceutical intermediates. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking efficient pathways for carbon-carbon bond formation and molecular diversification.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Employed in the manufacture of dyes, pigments, and specialty polymers requiring specific malonate-based structures.
• Heterocyclic Chemistry: Crucial reagent for constructing pyrimidines, pyridines, and other nitrogen-containing heterocycles via cyclocondensation reactions.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymeric materials with tailored properties.
• Academic & R&D Laboratories: Serves as a fundamental tool for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	Dimethyl (Hydroxymethylene)Malonate
CAS No.	27931-91-5
Molecular Formula	C6H8O5
Molecular Weight	160.12 g/mol
Synonyms	Dimethyl (hydroxymethylene)propanedioate; (Hydroxymethylene)malonic Acid Dimethyl Ester; Dimethyl Hydroxymethylenemalonate; Propanedioic acid, (hydroxymethylene)-, dimethyl ester; Formylmalonic Acid Dimethyl Ester; DMHM
EINECS	Contact for details

Quality Control

Our Dimethyl (Hydroxymethylene)Malonate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.