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Benzyl 2-O,3-O,4-o-Tribenzyl-β-D-Glucopyranosiduronic Acid Methyl Ester CAS NO 27851-32-7
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CAS No.:27851-32-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Benzyl 2-O,3-O,4-o-Tribenzyl-β-D-Glucopyranosiduronic Acid Methyl Ester is a protected derivative of glucuronic acid, a key intermediate in synthetic carbohydrate and medicinal chemistry. This compound is of significant value for its role in the controlled synthesis of complex oligosaccharides and glycoconjugates, where protecting groups are essential for regioselective reactions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of glycosidase inhibitors, prodrugs, and novel bioactive molecules.
Application
- Glycoscience Research: A crucial protected intermediate for the stepwise synthesis of complex oligosaccharides and glycans.
- Pharmaceutical Intermediate: Used in the research and development of glucuronide prodrugs to enhance drug solubility and targeting.
- Enzyme Inhibitor Synthesis: Serves as a building block for creating potential glycosidase and glucuronidase inhibitors.
- Glycoconjugate Preparation: Employed in the chemical synthesis of glycoproteins, glycolipids, and other biologically active conjugates.
- Standards and Reference Material: Used as a high-purity analytical standard in carbohydrate chemistry laboratories.
- Chemical Biology Probes: Acts as a precursor for labeled compounds used to study glycosylation pathways and enzyme mechanisms.
Basic Information
| Product Name | Benzyl 2-O,3-O,4-o-Tribenzyl-β-D-Glucopyranosiduronic Acid Methyl Ester |
| CAS No. | 27851-32-7 |
| Molecular Formula | C₃₅H₃₆O₈ |
| Molecular Weight | 584.66 g/mol |
| Synonyms | Methyl (benzyl 2,3,4-tri-O-benzyl-β-D-glucopyranosid)uronate; Benzyl 2,3,4-Tri-O-benzyl-β-D-glucopyranosiduronic Acid Methyl Ester; Methyl Benzyl 2,3,4-Tri-O-benzyl-1-thio-β-D-glucopyranosiduronate (related); Protected Methyl Glucuronate; Tribenzyl Glucuronic Acid Methyl Ester Benzyl Glycoside |
| EINECS | Contact for details |
Quality Control
Our Benzyl 2-O,3-O,4-o-Tribenzyl-β-D-Glucopyranosiduronic Acid Methyl Ester is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Specific Rotation | Contact for details |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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