Description

3-[3,4-Bis(Trimethylsilyloxy)Phenyl]Propionic Acid Methyl Ester is a specialized organosilicon-protected intermediate of significant value in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing active pharmaceutical ingredients (APIs) and other high-value targets.

Application

• Pharmaceutical Intermediate: A crucial protected synthon for the synthesis of complex drug molecules, particularly those containing catechol or dihydroxybenzene pharmacophores.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where the silyl-protected phenol moiety is required.
• Fine Chemical Production: Serves as a building block for creating specialty chemicals, flavors, and fragrances requiring controlled introduction of phenolic groups.
• Material Science Research: Employed in the development of novel polymers and advanced organic materials where silicon-containing aromatic monomers are incorporated.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, particularly in reactions involving silicon-based protecting group strategies.

Basic Information

Product Name	3-[3,4-Bis(Trimethylsilyloxy)Phenyl]Propionic Acid Methyl Ester
CAS No.	27798-75-0
Molecular Formula	C16H28O4Si2
Molecular Weight	340.57 g/mol
Synonyms	Methyl 3-[3,4-Bis(trimethylsilyloxy)phenyl]propionate; Methyl 3-(3,4-Bis((trimethylsilyl)oxy)phenyl)propanoate; 3,4-Bis-O-(trimethylsilyl)dihydrocaffeic acid methyl ester; Propanoic acid, 3-[3,4-bis[(trimethylsilyl)oxy]phenyl]-, methyl ester; Dihydrocaffeic acid 3,4-bis(trimethylsilyl) ether methyl ester
EINECS	Contact for details

Quality Control

Our 3-[3,4-Bis(Trimethylsilyloxy)Phenyl]Propionic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.