Description

p-[(Trimethylsilyl)Oxy]Hydrocinnamic Acid Methyl Ester is a specialized organosilicon-protected derivative of hydrocinnamic acid, serving as a valuable synthetic intermediate and protecting group reagent. Its core value lies in providing a stable, silyl-protected phenolic hydroxyl group, which is crucial for multi-step organic synthesis requiring selective deprotection. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex organic molecules where precise control over functional group reactivity is paramount.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, especially those requiring protected phenol functionalities.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for the preparation of fragrances, flavors, and advanced material precursors.
• Protecting Group Reagent: The trimethylsilyl (TMS) group acts as a protective moiety for phenolic -OH groups during synthetic sequences involving harsh reaction conditions.
• Research & Development: A critical reagent in academic and industrial R&D labs for exploring new synthetic methodologies and compound libraries.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides and plant growth regulators.
• Polymer Chemistry: Potential monomer or modifier in the synthesis of specialty silicon-containing polymers.

Basic Information

Product Name	p-[(Trimethylsilyl)Oxy]Hydrocinnamic Acid Methyl Ester
CAS No.	27798-74-9
Molecular Formula	C13H20O3Si
Molecular Weight	252.38 g/mol
Synonyms	Methyl 3-[4-(trimethylsilyloxy)phenyl]propanoate; Methyl 4-(Trimethylsiloxy)hydrocinnamate; 3-(4-Trimethylsiloxyphenyl)propionic Acid Methyl Ester; p-Trimethylsiloxyhydrocinnamic Acid Methyl Ester; Hydrocinnamic Acid, p-(Trimethylsilyloxy)-, Methyl Ester; Methyl (4-Trimethylsilyloxyphenyl)propionate; TMS-protected Methyl Hydrocinnamate; CAS 27798-74-9
EINECS	Contact for details

Quality Control

Our p-[(Trimethylsilyl)Oxy]Hydrocinnamic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply and consistent performance for your critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.