Description

3-[3,5-Dimethoxy-4-[(Trimethylsilyl)Oxy]Phenyl]Acrylic Acid Methyl Ester is a high-purity, functionalized cinnamate derivative featuring a silyl-protected phenolic group. This compound serves as a versatile synthetic intermediate and building block in advanced organic synthesis, offering a unique combination of reactivity and stability for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring protected phenolic functionalities.
• Organic Synthesis Reagent: Used in cross-coupling reactions, such as Heck reactions, and as a precursor for other functionalized cinnamic acid derivatives.
• Chemical Research: Serves as a model compound or starting material in academic and industrial research for developing new synthetic methodologies.
• Material Science Precursor: Potential use in the development of organic semiconductors, liquid crystals, or photoresponsive polymers due to its conjugated system.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and plant growth regulators.
• Flavor & Fragrance Chemistry: Used as a synthetic precursor for certain aromatic compounds in specialty chemical applications.

Basic Information

Product Name	3-[3,5-Dimethoxy-4-[(Trimethylsilyl)Oxy]Phenyl]Acrylic Acid Methyl Ester
CAS No.	27798-72-7
Molecular Formula	C15H22O5Si
Molecular Weight	310.42 g/mol
Synonyms	Methyl 3-(3,5-dimethoxy-4-((trimethylsilyl)oxy)phenyl)acrylate; Methyl (E)-3-(3,5-dimethoxy-4-((trimethylsilyl)oxy)phenyl)acrylate; 4-[(Trimethylsilyl)oxy]-3,5-dimethoxycinnamic acid methyl ester; 3,5-Dimethoxy-4-(trimethylsilyloxy)cinnamic acid methyl ester; TMS-protected sinapic acid methyl ester; Methyl 3-(4-hydroxy-3,5-dimethoxyphenyl)acrylate TMS ether; Sinapic acid methyl ester TMS ether
EINECS	Contact for details

Quality Control

Our 3-[3,5-Dimethoxy-4-[(Trimethylsilyl)Oxy]Phenyl]Acrylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.