Description

3,5-Bis[(Trimethylsilyl)Oxy]Benzoic Acid Methyl Ester is a high-purity, protected benzoic acid derivative featuring two trimethylsilyl (TMS) ether groups. This compound serves as a critical synthetic intermediate and protecting group reagent in advanced organic synthesis, offering enhanced stability and solubility for sensitive reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring protected phenolic functionalities.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or modifying agent in the production of specialized polymers and advanced organic materials.
• Organic Synthesis Reagent: Acts as a versatile protecting group for dihydroxybenzene structures in multi-step synthetic routes.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new reaction pathways.
• Liquid Crystal & OLED Materials: Potential intermediate in the synthesis of organic electronic materials due to its stable, derivatized aromatic core.

Basic Information

Product Name	3,5-Bis[(Trimethylsilyl)Oxy]Benzoic Acid Methyl Ester
CAS No.	27798-59-0
Molecular Formula	C15H26O5Si2
Molecular Weight	342.54 g/mol
Synonyms	Methyl 3,5-Bis(trimethylsiloxy)benzoate; Benzoic acid, 3,5-bis[(trimethylsilyl)oxy]-, methyl ester; Methyl 3,5-di-O-trimethylsilyloxybenzoate; 3,5-Di(trimethylsiloxy)benzoic Acid Methyl Ester; 3,5-Bis(trimethylsiloxy)methyl Benzoate; TMS-protected Methyl 3,5-Dihydroxybenzoate; Methyl 3,5-Bis(TMS-oxy)benzoate
EINECS	Contact for details

Quality Control

Our production of 3,5-Bis[(Trimethylsilyl)Oxy]Benzoic Acid Methyl Ester adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR). Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We operate under a cGMP-compliant quality management system to meet the exacting standards of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.