Description

3,4-Bis(Trimethylsiloxy)Benzoic Acid Methyl Ester is a specialized organosilicon compound that serves as a valuable protected intermediate in advanced organic synthesis. Its core value lies in the trimethylsilyl (TMS) protecting groups, which shield reactive hydroxyl functionalities, enabling precise and selective chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of complex molecules, active pharmaceutical ingredients (APIs), and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used as a protected intermediate in the production of specialty chemicals, agrochemicals, and advanced materials.
• Silicon Chemistry Research: A valuable reagent for studying silylation reactions and developing new organosilicon compounds.
• Polymer Modification: Can be utilized to introduce silyl-protected phenolic groups into polymer backbones for specialized material properties.
• Liquid Crystal & OLED Material Precursor: Serves as a synthetic intermediate for organic electronic materials requiring specific steric and electronic characteristics.

Basic Information

Product Name	3,4-Bis(Trimethylsiloxy)Benzoic Acid Methyl Ester
CAS No.	27798-58-9
Molecular Formula	C16H28O5Si2
Molecular Weight	356.56 g/mol
Synonyms	Methyl 3,4-Bis(trimethylsiloxy)benzoate; Benzoic acid, 3,4-bis[(trimethylsilyl)oxy]-, methyl ester; Methyl 3,4-dihydroxybenzoate bis(trimethylsilyl) ether; 3,4-Bis-O-(trimethylsilyl) methyl gallate; Methyl 3,4-bis(trimethylsiloxy)benzoate; 3,4-Di-O-trimethylsilyl methyl gallate
EINECS	Contact for details

Quality Control

Our 3,4-Bis(Trimethylsiloxy)Benzoic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance as a synthesis intermediate. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.