Description

2,6-Bis[(Trimethylsilyl)Oxy]Benzoic Acid Methyl Ester is a high-value, protected benzoic acid derivative featuring two trimethylsilyl (TMS) ether groups. This compound serves as a crucial synthetic intermediate and protecting group reagent in advanced organic synthesis, particularly for sensitive or multi-step reactions. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions developing novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially where selective protection of phenolic hydroxyl groups is required.
• Advanced Organic Synthesis: Used as a protected precursor for the preparation of substituted benzoic acids, esters, and other aromatic derivatives under harsh reaction conditions.
• Protecting Group Reagent: The TMS groups act as effective protecting agents for phenolic -OH functions, allowing for selective reactions at other sites on the molecule.
• Material Science Research: Potential monomer or intermediate in the development of specialized polymers, ligands, or organic electronic materials.
• Agrochemical Synthesis: Intermediate in the research and development of new herbicides, fungicides, or plant growth regulators with complex aromatic backbones.
• Academic & Process Chemistry: Valuable reagent for methodological studies, catalysis research, and scale-up process development in university and industrial labs.

Basic Information

Product Name	2,6-Bis[(Trimethylsilyl)Oxy]Benzoic Acid Methyl Ester
CAS No.	27798-57-8
Molecular Formula	C15H26O5Si2
Molecular Weight	342.54 g/mol
Synonyms	Methyl 2,6-Bis(trimethylsiloxy)benzoate; 2,6-Bis(trimethylsiloxy)benzoic Acid Methyl Ester; Benzoic acid, 2,6-bis[(trimethylsilyl)oxy]-, methyl ester; Methyl 2,6-di-O-trimethylsilylbenzoate; 2,6-Di(trimethylsiloxy)benzoic Acid Methyl Ester; 2,6-Bis(trimethylsilyloxy)benzoic Acid Methyl Ester; 2,6-Bis(TMS-oxy) Methyl Benzoate
EINECS	Contact for details

Quality Control

Our 2,6-Bis[(Trimethylsilyl)Oxy]Benzoic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.