Description

3-Methoxy-4-[(Trimethylsilyl)Oxy]Benzoic Acid Methyl Ester is a versatile organosilicon-protected phenolic ester, serving as a key synthetic intermediate in advanced organic chemistry. Its primary value lies in the trimethylsilyl (TMS) protecting group, which offers selective deprotection under mild conditions, enabling complex multi-step synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors, particularly for developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug molecules, especially those requiring selective protection and deprotection of phenolic hydroxyl groups.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, agrochemicals, and advanced materials where controlled reactivity is paramount.
• Organic Synthesis Research: Employed in academic and industrial R&D labs for developing novel synthetic pathways and methodologies.
• Liquid Crystal & Polymer Precursor: Acts as a monomer or intermediate in the synthesis of advanced polymers and liquid crystal materials.
• Flavor & Fragrance Ingredient Synthesis: Utilized as a precursor in the creation of complex aromatic compounds for the flavor and fragrance industry.

Basic Information

Product Name	3-Methoxy-4-[(Trimethylsilyl)Oxy]Benzoic Acid Methyl Ester
CAS No.	27798-53-4
Molecular Formula	C12H18O4Si
Molecular Weight	254.35 g/mol
Synonyms	Methyl 3-Methoxy-4-(trimethylsilyloxy)benzoate; Methyl 4-(Trimethylsiloxy)-3-methoxybenzoate; 4-(Trimethylsiloxy)-3-methoxybenzoic Acid Methyl Ester; Benzoic acid, 3-methoxy-4-[(trimethylsilyl)oxy]-, methyl ester; TMS-protected Methyl Vanillate; Methyl O-TMS Vanillate
EINECS	Contact for details

Quality Control

Our production of 3-Methoxy-4-[(Trimethylsilyl)Oxy]Benzoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. We offer material suitable for research and industrial synthesis, with specifications tailored to customer requirements. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.