Description

3-(Trimethylsiloxy)Benzoic Acid Methyl Ester is a specialized organosilicon compound that serves as a valuable intermediate in advanced organic synthesis. Its unique structure, featuring both a silyl ether and a methyl ester group, makes it a versatile building block for introducing functionalized benzoic acid derivatives into target molecules. This compound is particularly relevant for R&D chemists and process engineers in the pharmaceutical and fine chemical industries seeking to develop novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly those requiring silyl-protected phenolic or carboxylic acid functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the benzoate moiety is a core structural component.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing functionalized aromatic compounds used in electronic display technologies.
• Polymer Modification Agent: Employed to introduce siloxane and ester groups into polymer chains, modifying properties like solubility, adhesion, and thermal stability.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Stille) for constructing biaryl systems.
• Protecting Group Chemistry: The trimethylsiloxy group can act as a protecting group for phenols in multi-step synthetic sequences.

Basic Information

Product Name	3-(Trimethylsiloxy)Benzoic Acid Methyl Ester
CAS No.	27798-50-1
Molecular Formula	C11H16O3Si
Molecular Weight	224.33 g/mol
Synonyms	Methyl 3-(Trimethylsiloxy)benzoate; Benzoic acid, 3-(trimethylsiloxy)-, methyl ester; 3-(Trimethylsilyloxy)benzoic acid methyl ester; Methyl 3-hydroxybenzoate trimethylsilyl ether; 3-[(Trimethylsilyl)oxy]benzoic acid methyl ester; m-(Trimethylsiloxy)benzoic acid methyl ester; Trimethylsilyl 3-methoxycarbonylphenyl ether
EINECS	Contact for details

Quality Control

Our 3-(Trimethylsiloxy)Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.