Description

3-[3,4-Dimethoxyphenyl]Propenoic Acid Trimethylsilyl Ester is a high-purity, protected carboxylic acid derivative used as a critical synthetic intermediate. This compound matters for enabling complex organic synthesis, particularly in pharmaceutical research and fine chemical manufacturing, where its trimethylsilyl ester group offers enhanced stability and reactivity control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing dimethoxyphenyl motifs.
• Organic Synthesis Reagent: Used in coupling reactions, such as Heck reactions or Suzuki cross-couplings, where the protected acid functionality is required.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in asymmetric catalysis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers due to its conjugated system.
• Agrochemical Synthesis: Utilized as an intermediate in the production of certain herbicides and plant growth regulators.
• Flavor and Fragrance Chemistry: Acts as a precursor for synthesizing specific aroma chemicals with complex phenolic backbones.

Basic Information

Product Name	3-[3,4-Dimethoxyphenyl]Propenoic Acid Trimethylsilyl Ester
CAS No.	27750-71-6
Molecular Formula	C₁₄H₂₀O₄Si
Molecular Weight	280.40 g/mol
Synonyms	(E)-3-(3,4-Dimethoxyphenyl)acrylic acid trimethylsilyl ester; Trimethylsilyl 3-(3,4-dimethoxyphenyl)acrylate; 3,4-Dimethoxycinnamic acid trimethylsilyl ester; TMS 3,4-dimethoxycinnamate; (E)-Trimethylsilyl 3-(3,4-dimethoxyphenyl)propenoate; Propenoic acid, 3-(3,4-dimethoxyphenyl)-, trimethylsilyl ester; 27750-71-6
EINECS	Contact for details

Quality Control

Our 3-[3,4-Dimethoxyphenyl]Propenoic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to prevent moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.