Description

3,4-Di(Trimethylsiloxy)Hydrocinnamic Acid Trimethylsilyl Ester is a specialized organosilicon derivative of hydrocinnamic acid, featuring multiple trimethylsilyl protecting groups. This compound is valued for its role as a key synthetic intermediate and protecting group reagent in advanced organic synthesis, particularly for sensitive functional groups. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially those containing phenolic or carboxylic acid functionalities.
• Agrochemical Synthesis: Used in the development and production of advanced crop protection agents and herbicides where selective protection/deprotection strategies are required.
• Silicon-Based Protecting Group Reagent: Acts as an effective agent for introducing trimethylsilyl (TMS) protecting groups onto hydroxyl and carboxyl groups under mild conditions.
• Organic Synthesis Building Block: Provides a versatile scaffold for constructing more complex molecules in medicinal chemistry and material science research.
• Process Chemistry: Employed in route scouting and optimization for the scalable manufacture of fine chemicals and specialty materials.

Basic Information

Product Name	3,4-Di(Trimethylsiloxy)Hydrocinnamic Acid Trimethylsilyl Ester
CAS No.	27750-68-1
Molecular Formula	C18H34O4Si3
Molecular Weight	398.71 g/mol
Synonyms	Hydrocinnamic Acid, 3,4-Bis(trimethylsiloxy)-, Trimethylsilyl Ester; 3,4-Bis(trimethylsiloxy)hydrocinnamic Acid Trimethylsilyl Ester; Trimethylsilyl 3,4-Bis(trimethylsiloxy)hydrocinnamate; TMS-protected Dihydrocaffeic Acid Derivative; Silicon-protected Cinnamic Acid Ester
EINECS	Contact for details

Quality Control

Our 3,4-Di(Trimethylsiloxy)Hydrocinnamic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.