Description

3,4-Dimethoxybenzeneacetic Acid Trimethylsilyl Ester is a versatile organosilicon-protected intermediate of significant value in advanced organic synthesis. This compound is crucial for researchers and manufacturers requiring a stable, silylated derivative of 3,4-dimethoxyphenylacetic acid for sensitive reactions. It is primarily utilized in the development of pharmaceuticals, agrochemicals, and fine chemicals, where protecting group chemistry is essential for selective transformations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those with catechol or dimethoxyphenyl pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a protected precursor for fragrances, flavors, and specialty polymers.
• Organic Synthesis Research: Employed in academic and industrial R&D for methodologies involving silyl ester protection and deprotection strategies.
• Ligand and Catalyst Preparation: Useful in the synthesis of specialized ligands for metal-catalyzed cross-coupling reactions.

Basic Information

Product Name	3,4-Dimethoxybenzeneacetic Acid Trimethylsilyl Ester
CAS No.	27750-60-3
Molecular Formula	C₁₃H₂₀O₄Si
Molecular Weight	268.38 g/mol
Synonyms	3,4-Dimethoxyphenylacetic Acid Trimethylsilyl Ester; (3,4-Dimethoxyphenyl)acetic Acid Trimethylsilyl Ester; Trimethylsilyl 2-(3,4-Dimethoxyphenyl)acetate; TMS-DMPA Ester; Veratric Acid Trimethylsilyl Ester; 27750-60-3; Acetic acid, 2-(3,4-dimethoxyphenyl)-, trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our 3,4-Dimethoxybenzeneacetic Acid Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent hydrolysis. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.