Description

α-[(Trimethylsilyl)Oxy]Benzenepropionic Acid Trimethylsilyl Ester is a high-purity, protected intermediate crucial for advanced organic synthesis. This compound is valued for its role in introducing silyl-protected functional groups, enabling complex multi-step reactions with high selectivity and yield. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the production of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators.
• Peptide & Protein Chemistry: Serves as a protected carboxylic acid derivative in solid-phase peptide synthesis (SPPS).
• Material Science Research: Intermediate for creating functionalized polymers and advanced organic materials.
• Academic & Industrial R&D: Essential reagent for methodological development and exploratory organic synthesis in laboratory settings.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring precise molecular architecture.

Basic Information

Product Name	α-[(Trimethylsilyl)Oxy]Benzenepropionic Acid Trimethylsilyl Ester
CAS No.	27750-45-4
Molecular Formula	C15H26O3Si2
Molecular Weight	310.54 g/mol
Synonyms	3-[2-(Trimethylsilyloxy)phenyl]propanoic acid trimethylsilyl ester; 2-(Trimethylsiloxy)hydrocinnamic acid trimethylsilyl ester; Benzenepropanoic acid, α-[(trimethylsilyl)oxy]-, trimethylsilyl ester; TMS-protected hydrocinnamic acid derivative; Silyl ester of α-(trimethylsiloxy)benzenepropanoic acid
EINECS	Contact for details

Quality Control

Our α-[(Trimethylsilyl)Oxy]Benzenepropionic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.