Description

4-[(Trimethylsilyl)Oxy]Benzoic Acid Propyl Ester is a specialized organosilicon-protected derivative of para-hydroxybenzoic acid. This compound is valued for its role as a versatile synthetic intermediate and protecting group in advanced organic synthesis, particularly in pharmaceutical and fine chemical research. It is primarily needed by R&D chemists and process development scientists working on complex molecules where selective protection and deprotection strategies are critical.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially where phenolic OH groups require temporary protection.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for fragrances, liquid crystals, and advanced polymer precursors.
• Protecting Group Reagent: The trimethylsilyl (TMS) group offers a stable, yet cleavable, protection for phenolic hydroxyl groups under mild conditions.
• Material Science Research: Intermediate in the development of specialty monomers for silicone-modified polymers and coatings.
• Academic & Industrial R&D: Serves as a valuable reagent in methodological development and scale-up chemistry within research laboratories.

Basic Information

Product Name	4-[(Trimethylsilyl)Oxy]Benzoic Acid Propyl Ester
CAS No.	27739-19-1
Molecular Formula	C13H20O3Si
Molecular Weight	252.38 g/mol
Synonyms	Propyl 4-(Trimethylsilyloxy)benzoate; 4-(Trimethylsiloxy)benzoic Acid Propyl Ester; Benzoic acid, 4-[(trimethylsilyl)oxy]-, propyl ester; p-(Trimethylsilyloxy)benzoic Acid Propyl Ester; Propyl p-(Trimethylsilyloxy)benzoate; TMS-protected Propyl Paraben; Propyl 4-Hydroxybenzoate Trimethylsilyl Ether
EINECS	Contact for details

Quality Control

Our 4-[(Trimethylsilyl)Oxy]Benzoic Acid Propyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of industrial and research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.