Description

4-(Trimethylsiloxy)Benzoic Acid Methyl Ester is a specialized organosilicon derivative of methyl salicylate, valued for its role as a versatile synthetic intermediate and protecting group in advanced organic synthesis. Its unique trimethylsiloxy moiety imparts specific reactivity and stability, making it a critical reagent for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for fine chemical production.

Application

• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring silyl-protected phenolic groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its silicon-containing group modifies bioavailability and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of silicon-based organic electronic materials and liquid crystal compounds.
• Polymer & Resin Modifiers: Employed to introduce siloxy functional groups into polymer chains, enhancing thermal stability, adhesion, or surface properties.
• Flavor & Fragrance Chemistry: Acts as a protected intermediate in the multi-step synthesis of complex aromatic esters and odorants.
• Organic Synthesis Reagent: Utilized as a versatile silylating agent and protecting group for carboxylic acids and phenols in complex multi-step laboratory syntheses.

Basic Information

Product Name	4-(Trimethylsiloxy)Benzoic Acid Methyl Ester
CAS No.	27739-17-9
Molecular Formula	C11H16O3Si
Molecular Weight	224.33 g/mol
Synonyms	Methyl 4-(trimethylsiloxy)benzoate; Methyl 4-(trimethylsilyloxy)benzoate; 4-(Trimethylsilyloxy)benzoic acid methyl ester; Benzoic acid, 4-(trimethylsiloxy)-, methyl ester; p-(Trimethylsiloxy)benzoic acid methyl ester; Methyl p-(trimethylsiloxy)benzoate; TMS-protected methyl salicylate derivative
EINECS	Contact for details

Quality Control

Our production of 4-(Trimethylsiloxy)Benzoic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Refractive Index	1.490 - 1.510
Density	1.05 - 1.10 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.