Description

n-Chlorocarbonyl Isocyanate is a highly reactive bifunctional reagent that serves as a versatile building block for the synthesis of complex heterocyclic and carbamate structures. Its core value lies in enabling the efficient, one-step introduction of both an isocyanate and an acid chloride functional group, facilitating the creation of novel pharmacophores and advanced materials. This compound is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of ureas, carbamates, and heterocycles like hydantoins and barbiturates, which are core structures in numerous active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where it contributes to the carbamate or urea moiety of the active molecule.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing polyurethanes, polyureas, and other specialty polymers with tailored properties.
• Peptide Modification: Employed to introduce isocyanate-derived protecting groups or to create novel amino acid analogs for peptide-based drug discovery.
• Chemical Research & Development: A valuable tool for academic and industrial researchers exploring new reaction pathways and synthesizing novel chemical entities for screening libraries.
• Dye and Pigment Manufacturing: Used in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	n-Chlorocarbonyl Isocyanate
CAS No.	27738-96-1
Molecular Formula	C2ClNO2
Molecular Weight	105.48 g/mol
Synonyms	Chlorocarbonyl isocyanate; Carbonochloridic acid, isocyanate; Isocyanatocarbonyl chloride; Chloroformyl isocyanate; NSC 93776; Isocyanatoformyl chloride; Carbamoyl chloride, N-carbonyl-; Carbonyl chloride isocyanate
EINECS	Contact for details

Quality Control

Our n-Chlorocarbonyl Isocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profile. We adhere to cGMP standards where applicable, and our quality system is designed to meet the rigorous demands of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.