Description

4-Hydroxyphenylacetic Acid Benzyl Ester is a versatile aromatic ester derivative of phenylacetic acid, serving as a crucial protected intermediate in advanced organic synthesis. Its value lies in providing a stable, benzyl-protected phenolic group, enabling selective reactions in complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, including potential anti-inflammatory and analgesic agents.
• Peptide Synthesis: Used as a protecting group reagent for tyrosine and other phenolic amino acids during solid-phase and solution-phase peptide synthesis.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, fragrances, and advanced polymer precursors.
• Agrochemical Research: Serves as a starting material or intermediate in the development of novel herbicides and plant growth regulators.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research projects.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with specific optical or thermal properties.

Basic Information

Product Name	4-Hydroxyphenylacetic Acid Benzyl Ester
CAS No.	27727-37-3
Molecular Formula	C15H14O3
Molecular Weight	242.27 g/mol
Synonyms	Benzyl 4-Hydroxyphenylacetate; Benzyl (4-Hydroxyphenyl)acetate; 4-Hydroxybenzeneacetic Acid Benzyl Ester; (4-Hydroxyphenyl)acetic Acid Benzyl Ester; p-Hydroxyphenylacetic Acid Benzyl Ester; Benzyl p-Hydroxyphenylacetate; 27727-37-3; NSC 403714
EINECS	Contact for details

Quality Control

Our 4-Hydroxyphenylacetic Acid Benzyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.