Description

Ethyl 3-(Hydroxymethyl)Cyclobutane-1-Carboxylate is a high-purity, multifunctional cyclobutane derivative of significant interest in advanced organic synthesis. This compound serves as a versatile chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing constrained ring systems with precise stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly those requiring a rigid, four-membered carbocyclic scaffold.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides where the cyclobutane structure imparts unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and functional materials with tailored properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, stereodefined intermediates.

Basic Information

Product Name	Ethyl 3-(Hydroxymethyl)Cyclobutane-1-Carboxylate
CAS No.	27697-61-6
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Ethyl 3-(hydroxymethyl)cyclobutanecarboxylate; 3-(Hydroxymethyl)cyclobutanecarboxylic Acid Ethyl Ester; 1-Carbethoxy-3-hydroxymethylcyclobutane; Cyclobutanecarboxylic acid, 3-(hydroxymethyl)-, ethyl ester; Ethyl 3-hydroxymethylcyclobutanecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Hydroxymethyl)Cyclobutane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and current Good Manufacturing Practice (cGMP) principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.